The effects of therapeutic hypothermia on term infants with neonatal asphyxial encephalopathy

Abstract 

Therapeutic hypothermia in term infants with neonatal asphyxial encephalopathy has been shown to have beneficial effects in relation to neurodevelopmental outcome and survival. This paper is a critical appraisal of two studies, which compares and contrasts the methodology and findings, and incorporates a synthesis of findings with reflection on clinical practice.

Keywords: Therapeutic hypothermia, Neonatal hypoxia, Critical appraisal, Application to neonatal practice